Myrlande Constant is known for her striking beaded and sequin-embellished textile artworks. Since she began making drapo Vodou (Vodou flags) in the 1990s, she has transformed and surpassed this medium, preferring to make large-scale tableau; she describes her work as "painting with beads."
In 2023, the solo exhibition Myrlande Constant: The Work of Radiance was presented at the Fowler Museum, Los Angeles, CA. Constant’s artwork was featured in The Milk of Dreams, 59th International Art Exhibition of La Biennale di Venezia, Italy in 2022. Her artwork is included in various museum collections, including the Art Institute of Chicago, IL; de Young Museum, Fine Arts Museums of San Francisco, CA; Figge Art Museum, Davenport, Iowa; Fowler Museum, UCLA, CA; High Museum of Art, Atlanta, GA; Institute of Contemporary Art, Miami, FL; Minneapolis Institute of Art, MN; Museum of Contemporary Art Chicago, IL; National Gallery of Art, Washington, DC; New Orleans Museum of Art, LA; Pérez Art Museum, Miami, FL; RISD Museum, Rhode Island School of Design, Providence, RI; Tampa Museum of Art, FL; Waterloo Center for the Arts, IA; and Worcester Art Museum, MA; among others.